Сравнение

Selank vs. Sincalide

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Исследования (прочее)

Номер CAS

129954-34-3

25126-32-3

Молекулярная масса

751.85 g/mol

1143.29 g/mol

Период полувыведения

0.3 h

нет данных

Последовательность

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

Механизм действия

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Sincalide

Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).

Доказательная база

Наивысшая доказательность

Исследование на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	Selank	Sincalide
Германия	Не одобрено	Неясно
RU	Рецептурный	—
США	Не одобрено	Рецептурный

Полные записи

Frequently asked questions

What is the difference between Selank and Sincalide?: Selank is classified as "Исследования (прочее)", while Sincalide is classified as "Исследования (прочее)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Sincalide?: The highest available evidence level is "Исследование на людях" for Selank and "Исследование на людях" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Sincalide in Germany and the United States?: Германия: Selank — Не одобрено, Sincalide — Неясно. США: Selank — Не одобрено, Sincalide — Рецептурный. These are factual summaries with source and review date on the individual pages.

Country

Selank

Sincalide

Германия

Не одобрено

Неясно

Рецептурный

—

США

Не одобрено

Рецептурный

Frequently asked questions

What is the difference between Selank and Sincalide?

Selank is classified as "Исследования (прочее)", while Sincalide is classified as "Исследования (прочее)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Sincalide?

The highest available evidence level is "Исследование на людях" for Selank and "Исследование на людях" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Sincalide in Germany and the United States?

Германия: Selank — Не одобрено, Sincalide — Неясно. США: Selank — Не одобрено, Sincalide — Рецептурный. These are factual summaries with source and review date on the individual pages.