Confronto

Selank vs. Sincalide

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Ricerca (altro)

N. CAS

129954-34-3

25126-32-3

Peso molecolare

751.85 g/mol

1143.29 g/mol

Emivita

0.3 h

nessun dato

Sequenza

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

Meccanismo d'azione

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Sincalide

Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).

Base di evidenze

Evidenza più alta

Studio sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Selank	Sincalide
Germania	Non approvato	Non chiaro
RU	Su prescrizione	—
Stati Uniti	Non approvato	Su prescrizione

Voci complete

Frequently asked questions

What is the difference between Selank and Sincalide?: Selank is classified as "Ricerca (altro)", while Sincalide is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Sincalide?: The highest available evidence level is "Studio sull'uomo" for Selank and "Studio sull'uomo" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Sincalide in Germany and the United States?: Germania: Selank — Non approvato, Sincalide — Non chiaro. Stati Uniti: Selank — Non approvato, Sincalide — Su prescrizione. These are factual summaries with source and review date on the individual pages.

Country

Selank

Sincalide

Germania

Non approvato

Non chiaro

Su prescrizione

—

Stati Uniti

Non approvato

Su prescrizione

Frequently asked questions

What is the difference between Selank and Sincalide?

Selank is classified as "Ricerca (altro)", while Sincalide is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Sincalide?

The highest available evidence level is "Studio sull'uomo" for Selank and "Studio sull'uomo" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Sincalide in Germany and the United States?

Germania: Selank — Non approvato, Sincalide — Non chiaro. Stati Uniti: Selank — Non approvato, Sincalide — Su prescrizione. These are factual summaries with source and review date on the individual pages.