Сравнение
Selank vs. Teduglutid
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
129954-34-3
197922-42-2
Молекулярная масса
751.85 g/mol
3752.13 g/mol
Период полувыведения
0.3 h
нет данных
Последовательность
Thr-Lys-Pro-Arg-Pro-Gly-Proнет данных
Механизм действия
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Teduglutid
Teduglutide activates the GLP-2 receptor, promoting growth and regeneration of small-intestinal villi, increasing nutrient and fluid absorption and thereby reducing dependence on parenteral nutrition. The glycine substitution at position 2 makes it resistant to rapid breakdown by DPP-4.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
4
2
из них на людях
2
2
Зафиксированные эффекты
3
2
Открытые противоречия
1
0
Задокументированные нежелательные явления
1
2
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Selank and Teduglutid?
- Selank is classified as "Исследования (прочее)", while Teduglutid is classified as "Исследования (прочее)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Teduglutid: Teduglutide is a DPP-4-resistant analog of GLP-2 (glucagon-like peptide-2). It promotes growth and function of the intestinal mucosa and is approved for treating short bowel syndrome. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Teduglutid?
- The highest available evidence level is "Исследование на людях" for Selank and "РКИ на людях" for Teduglutid. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Teduglutid in Germany and the United States?
- Германия: Selank — Не одобрено, Teduglutid — Рецептурный. США: Selank — Не одобрено, Teduglutid — Рецептурный. These are factual summaries with source and review date on the individual pages.