Сравнение
Tirzepatide vs. VK2735
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Метаболизм
Метаболизм
Номер CAS
2023788-19-2
нет данных
Молекулярная масса
4813 g/mol
нет данных
Период полувыведения
116 h
нет данных
Последовательность
YXEGTFTSDYSIYLDKIAQKAFVQWLIAGGPSSGAPPPSнет данных
Механизм действия
Tirzepatide
Tirzepatide is a 39-amino-acid peptide acting as a dual agonist at the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. Activation of both incretin receptors via G-protein-coupled signalling raises insulin secretion in a glucose-dependent manner, lowers glucagon secretion and delays gastric emptying. Centrally, satiety perception is modulated. A fatty-acid side chain binds to serum albumin and extends the half-life to about five days.
VK2735
VK2735 activates both the GLP-1 and the GIP receptor — a dual mechanism similar to that of tirzepatide, suppressing appetite and food intake.
Доказательная база
Наивысшая доказательность
РКИ на людях
РКИ на людях
Исследования
4
1
из них на людях
4
1
Зафиксированные эффекты
4
2
Открытые противоречия
1
0
Задокументированные нежелательные явления
2
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Tirzepatide and VK2735?
- Tirzepatide is classified as "Метаболизм", while VK2735 is classified as "Метаболизм". Tirzepatide: Synthetic peptide that simultaneously activates the GLP-1 and GIP receptor (dual agonist). Approved in the US and EU for type 2 diabetes (Mounjaro) and obesity (Zepbound). VK2735: VK2735 is a dual GLP-1/GIP receptor agonist from Viking Therapeutics, in development in both subcutaneous and oral forms for obesity. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Tirzepatide or VK2735?
- The highest available evidence level is "РКИ на людях" for Tirzepatide and "РКИ на людях" for VK2735. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Tirzepatide and VK2735 in Germany and the United States?
- Германия: Tirzepatide — Рецептурный, VK2735 — Не одобрено. США: Tirzepatide — Рецептурный, VK2735 — Не одобрено. These are factual summaries with source and review date on the individual pages.