Vergelijking
CJC-1295 vs. GHRP-2
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Groei
Groei
CAS-nr.
geen gegevens
158861-67-7
Molecuulmassa
3647.3 g/mol
817.93 g/mol
Halfwaardetijd
144 h
0.5 h
Sequentie
YADAIFTNSYRKVLGQLSARKLLQDIMSR-DACD-Ala-D-2-Naphthyl-Ala-Ala-Trp-D-Phe-Lys-NH2Werkingsmechanisme
CJC-1295
Synthetic analogue of growth-hormone-releasing hormone (GHRH), modified for extended half-life via a Drug Affinity Complex (DAC) binding to albumin. Acts on the pituitary GHRH receptor and stimulates endogenous growth-hormone release.
GHRP-2
GHRP-2 binds with high affinity to the GH secretagogue receptor (GHSR-1a) in the pituitary and hypothalamus. Activation leads to rapid release of pulsatile growth hormone. Unlike GHRH, GHRP-2 acts via a separate pathway and can be combined synergistically with GHRH to elicit maximal GH responses in provocation tests.
Bewijsbasis
Hoogste bewijs
Humane studie
Humane studie
Studies
4
4
waarvan bij mensen
3
4
Geregistreerde effecten
3
3
Openstaande tegenstrijdigheden
1
0
Gedocumenteerde bijwerkingen
3
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between CJC-1295 and GHRP-2?
- CJC-1295 is classified as "Groei", while GHRP-2 is classified as "Groei". CJC-1295: Long-acting synthetic GHRH analogue modified for albumin binding (DAC). Stimulates endogenous growth-hormone release. Pharmacodynamic effect established in small human studies; clinical endpoint trials are missing. GHRP-2: Synthetic hexapeptide of the GH secretagogue family. Approved in Japan as GHRP Kaken as a diagnostic test for GH deficiency. Not available as a medicine outside Japan. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, CJC-1295 or GHRP-2?
- The highest available evidence level is "Humane studie" for CJC-1295 and "Humane studie" for GHRP-2. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of CJC-1295 and GHRP-2 in Germany and the United States?
- Duitsland: CJC-1295 — Niet goedgekeurd, GHRP-2 — Niet goedgekeurd. Verenigde Staten: CJC-1295 — Alleen onderzoek, GHRP-2 — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.