Vergelijking
Teduglutid vs. Vasopressin
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
197922-42-2
geen gegevens
Molecuulmassa
3752.13 g/mol
1084.23 g/mol
Halfwaardetijd
geen gegevens
geen gegevens
Sequentie
geen gegevens
geen gegevens
Werkingsmechanisme
Teduglutid
Teduglutide activates the GLP-2 receptor, promoting growth and regeneration of small-intestinal villi, increasing nutrient and fluid absorption and thereby reducing dependence on parenteral nutrition. The glycine substitution at position 2 makes it resistant to rapid breakdown by DPP-4.
Vasopressin
Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane RCT
Studies
2
0
waarvan bij mensen
2
0
Geregistreerde effecten
2
2
Openstaande tegenstrijdigheden
0
0
Gedocumenteerde bijwerkingen
2
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Teduglutid and Vasopressin?
- Teduglutid is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Teduglutid: Teduglutide is a DPP-4-resistant analog of GLP-2 (glucagon-like peptide-2). It promotes growth and function of the intestinal mucosa and is approved for treating short bowel syndrome. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Teduglutid or Vasopressin?
- The highest available evidence level is "Humane RCT" for Teduglutid and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Teduglutid and Vasopressin in Germany and the United States?
- Duitsland: Teduglutid — Op recept, Vasopressin — Op recept. Verenigde Staten: Teduglutid — Op recept, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.