Comparison
Teduglutid vs. Vasopressin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Research other
Research other
CAS no.
197922-42-2
no data
Molecular weight
3752.13 g/mol
1084.23 g/mol
Half-life
no data
no data
Sequence
no data
no data
Mechanism of action
Teduglutid
Teduglutide activates the GLP-2 receptor, promoting growth and regeneration of small-intestinal villi, increasing nutrient and fluid absorption and thereby reducing dependence on parenteral nutrition. The glycine substitution at position 2 makes it resistant to rapid breakdown by DPP-4.
Vasopressin
Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.
Evidence base
Highest evidence
Human RCT
Human RCT
Studies
2
0
of which in humans
2
0
Effects recorded
2
2
Open conflicts
0
0
Documented adverse events
2
1
Legal status
Full entries
Frequently asked questions
- What is the difference between Teduglutid and Vasopressin?
- Teduglutid is classified as "Research other", while Vasopressin is classified as "Research other". Teduglutid: Teduglutide is a DPP-4-resistant analog of GLP-2 (glucagon-like peptide-2). It promotes growth and function of the intestinal mucosa and is approved for treating short bowel syndrome. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Teduglutid or Vasopressin?
- The highest available evidence level is "Human RCT" for Teduglutid and "Human RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Teduglutid and Vasopressin in Germany and the United States?
- Germany: Teduglutid — Prescription, Vasopressin — Prescription. United States: Teduglutid — Prescription, Vasopressin — Prescription. These are factual summaries with source and review date on the individual pages.