Сравнение

TB-500 vs. Thymosin Alpha-1

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Заживление

Номер CAS

нет данных

62304-98-7

Молекулярная масса

888 g/mol

3108.32 g/mol

Период полувыведения

нет данных

2 h

Последовательность

Ac-LKKTETQ

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN

Механизм действия

TB-500

Synthetic fragment of the endogenous protein Thymosin Beta-4. In preclinical models, an influence on cell migration, actin sequestration and neovascularisation has been described. Robust human pharmacokinetic data are not publicly available.

Thymosin Alpha-1

Thymosin Alpha-1 is an N-terminally acetylated peptide originally isolated from the thymus. It modulates T-lymphocyte maturation and function and acts on dendritic cells via Toll-like receptors (TLR9 / TLR2). In preclinical and some clinical studies, increased interferon-gamma responses and altered T-cell subpopulations have been reported.

Доказательная база

Наивысшая доказательность

Модель на животных

РКИ на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	TB-500	Thymosin Alpha-1
Австралия	Запрещено	—
Германия	Не одобрено	Не одобрено
IT	—	Рецептурный
США	Только для исследований	Не одобрено

Полные записи

Frequently asked questions

What is the difference between TB-500 and Thymosin Alpha-1?: TB-500 is classified as "Заживление", while Thymosin Alpha-1 is classified as "Заживление". TB-500: Synthetic fragment of the endogenous protein Thymosin Beta-4, specifically the actin-binding sequence. Preclinical models investigate effects on cell migration, neovascularisation and wound healing — robust human data are absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, TB-500 or Thymosin Alpha-1?: The highest available evidence level is "Модель на животных" for TB-500 and "РКИ на людях" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of TB-500 and Thymosin Alpha-1 in Germany and the United States?: Германия: TB-500 — Не одобрено, Thymosin Alpha-1 — Не одобрено. США: TB-500 — Только для исследований, Thymosin Alpha-1 — Не одобрено. These are factual summaries with source and review date on the individual pages.

Country

TB-500

Thymosin Alpha-1

Австралия

Запрещено

—

Германия

Не одобрено

—

Рецептурный

США

Только для исследований

Не одобрено

Frequently asked questions

What is the difference between TB-500 and Thymosin Alpha-1?

TB-500 is classified as "Заживление", while Thymosin Alpha-1 is classified as "Заживление". TB-500: Synthetic fragment of the endogenous protein Thymosin Beta-4, specifically the actin-binding sequence. Preclinical models investigate effects on cell migration, neovascularisation and wound healing — robust human data are absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, TB-500 or Thymosin Alpha-1?

The highest available evidence level is "Модель на животных" for TB-500 and "РКИ на людях" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of TB-500 and Thymosin Alpha-1 in Germany and the United States?

Германия: TB-500 — Не одобрено, Thymosin Alpha-1 — Не одобрено. США: TB-500 — Только для исследований, Thymosin Alpha-1 — Не одобрено. These are factual summaries with source and review date on the individual pages.