Confronto
TB-500 vs. Thymosin Alpha-1
Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.
Identità
Categoria
Guarigione
Guarigione
N. CAS
nessun dato
62304-98-7
Peso molecolare
888 g/mol
3108.32 g/mol
Emivita
nessun dato
2 h
Sequenza
Ac-LKKTETQAc-SDAAVDTSSEITTKDLKEKKEVVEEAENMeccanismo d'azione
TB-500
Synthetic fragment of the endogenous protein Thymosin Beta-4. In preclinical models, an influence on cell migration, actin sequestration and neovascularisation has been described. Robust human pharmacokinetic data are not publicly available.
Thymosin Alpha-1
Thymosin Alpha-1 is an N-terminally acetylated peptide originally isolated from the thymus. It modulates T-lymphocyte maturation and function and acts on dendritic cells via Toll-like receptors (TLR9 / TLR2). In preclinical and some clinical studies, increased interferon-gamma responses and altered T-cell subpopulations have been reported.
Base di evidenze
Evidenza più alta
Modello animale
RCT sull'uomo
Studi
3
4
di cui sull'uomo
0
4
Effetti registrati
4
3
Contraddizioni aperte
1
1
Eventi avversi documentati
2
1
Stato legale
Voci complete
Frequently asked questions
- What is the difference between TB-500 and Thymosin Alpha-1?
- TB-500 is classified as "Guarigione", while Thymosin Alpha-1 is classified as "Guarigione". TB-500: Synthetic fragment of the endogenous protein Thymosin Beta-4, specifically the actin-binding sequence. Preclinical models investigate effects on cell migration, neovascularisation and wound healing — robust human data are absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, TB-500 or Thymosin Alpha-1?
- The highest available evidence level is "Modello animale" for TB-500 and "RCT sull'uomo" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of TB-500 and Thymosin Alpha-1 in Germany and the United States?
- Germania: TB-500 — Non approvato, Thymosin Alpha-1 — Non approvato. Stati Uniti: TB-500 — Solo ricerca, Thymosin Alpha-1 — Non approvato. These are factual summaries with source and review date on the individual pages.