Vergelijking

TB-500 vs. Thymosin Alpha-1

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Genezing

CAS-nr.

geen gegevens

62304-98-7

Molecuulmassa

888 g/mol

3108.32 g/mol

Halfwaardetijd

geen gegevens

2 h

Sequentie

Ac-LKKTETQ

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN

Werkingsmechanisme

TB-500

Synthetic fragment of the endogenous protein Thymosin Beta-4. In preclinical models, an influence on cell migration, actin sequestration and neovascularisation has been described. Robust human pharmacokinetic data are not publicly available.

Thymosin Alpha-1

Thymosin Alpha-1 is an N-terminally acetylated peptide originally isolated from the thymus. It modulates T-lymphocyte maturation and function and acts on dendritic cells via Toll-like receptors (TLR9 / TLR2). In preclinical and some clinical studies, increased interferon-gamma responses and altered T-cell subpopulations have been reported.

Bewijsbasis

Hoogste bewijs

Diermodel

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	TB-500	Thymosin Alpha-1
Australië	Verboden	—
Duitsland	Niet goedgekeurd	Niet goedgekeurd
IT	—	Op recept
Verenigde Staten	Alleen onderzoek	Niet goedgekeurd

Volledige vermeldingen

TB-500

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Thymosin Alpha-1

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Frequently asked questions

What is the difference between TB-500 and Thymosin Alpha-1?: TB-500 is classified as "Genezing", while Thymosin Alpha-1 is classified as "Genezing". TB-500: Synthetic fragment of the endogenous protein Thymosin Beta-4, specifically the actin-binding sequence. Preclinical models investigate effects on cell migration, neovascularisation and wound healing — robust human data are absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, TB-500 or Thymosin Alpha-1?: The highest available evidence level is "Diermodel" for TB-500 and "Humane RCT" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of TB-500 and Thymosin Alpha-1 in Germany and the United States?: Duitsland: TB-500 — Niet goedgekeurd, Thymosin Alpha-1 — Niet goedgekeurd. Verenigde Staten: TB-500 — Alleen onderzoek, Thymosin Alpha-1 — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.

Country

TB-500

Thymosin Alpha-1

Australië

Verboden

—

Duitsland

Niet goedgekeurd

—

Op recept

Verenigde Staten

Alleen onderzoek

Niet goedgekeurd

Frequently asked questions

What is the difference between TB-500 and Thymosin Alpha-1?

TB-500 is classified as "Genezing", while Thymosin Alpha-1 is classified as "Genezing". TB-500: Synthetic fragment of the endogenous protein Thymosin Beta-4, specifically the actin-binding sequence. Preclinical models investigate effects on cell migration, neovascularisation and wound healing — robust human data are absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, TB-500 or Thymosin Alpha-1?

The highest available evidence level is "Diermodel" for TB-500 and "Humane RCT" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of TB-500 and Thymosin Alpha-1 in Germany and the United States?

Duitsland: TB-500 — Niet goedgekeurd, Thymosin Alpha-1 — Niet goedgekeurd. Verenigde Staten: TB-500 — Alleen onderzoek, Thymosin Alpha-1 — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.