Comparison
BPC-157 vs. Epitalon
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Research other
CAS no.
137525-51-0
307297-39-8
Molecular weight
1419.5 g/mol
390.35 g/mol
Half-life
4 h
0.3 h
Sequence
GEPPPGKPADDAGLVAla-Glu-Asp-GlyMechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Epitalon
Postulated mechanisms include modulation of gene expression in pinealocytes, telomerase activation (observed in cell culture studies) and influence on melatonin synthesis. A defined primary receptor is not established; the mechanistic basis rests on in-vitro and animal data from the Khavinson group.
Evidence base
Highest evidence
Animal model
Human trial
Studies
4
4
of which in humans
0
1
Effects recorded
4
4
Open conflicts
2
1
Documented adverse events
2
1