Comparison
BPC-157 vs. Sermorelin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Growth
CAS no.
137525-51-0
86168-78-7
Molecular weight
1419.5 g/mol
3358 g/mol
Half-life
4 h
0.2 h
Sequence
GEPPPGKPADDAGLVYADAIFTNSYRKVLGQLSARKLLQDIMSRMechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Sermorelin
Synthetic analogue of the first 29 amino acids of human growth-hormone-releasing hormone (GHRH). Stimulates pulsatile endogenous growth-hormone secretion from the pituitary via the GHRH receptor. Very short plasma half-life — pharmacodynamic effect lasts several hours nevertheless.
Evidence base
Highest evidence
Animal model
Human RCT
Studies
4
5
of which in humans
0
3
Effects recorded
4
3
Open conflicts
2
1
Documented adverse events
2
3