Comparison
BPC-157 vs. Hexarelin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Growth
CAS no.
137525-51-0
140703-51-1
Molecular weight
1419.5 g/mol
887.05 g/mol
Half-life
4 h
0.9 h
Sequence
GEPPPGKPADDAGLVHis-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2Mechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
Evidence base
Highest evidence
Animal model
Human trial
Studies
4
4
of which in humans
0
3
Effects recorded
4
3
Open conflicts
2
0
Documented adverse events
2
1