Comparison
BPC-157 vs. Selank
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Research other
CAS no.
137525-51-0
129954-34-3
Molecular weight
1419.5 g/mol
751.85 g/mol
Half-life
4 h
0.3 h
Sequence
GEPPPGKPADDAGLVThr-Lys-Pro-Arg-Pro-Gly-ProMechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Evidence base
Highest evidence
Animal model
Human trial
Studies
4
4
of which in humans
0
2
Effects recorded
4
3
Open conflicts
2
0
Documented adverse events
2
1