Comparison
BPC-157 vs. Thymalin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Healing
CAS no.
137525-51-0
63958-90-7
Molecular weight
1419.5 g/mol
1000 g/mol
Half-life
4 h
0.5 h
Sequence
GEPPPGKPADDAGLVno data
Mechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Thymalin
Thymalin is a complex of multiple polypeptides extracted from bovine or calf thymus. Postulated mechanisms include modulation of T-lymphocyte maturation, influence on interleukin profiles and stimulation of cellular immune response. Being a multi-component preparation, individual mechanisms are difficult to disentangle. Khavinson and colleagues from St Petersburg have described the mechanism over decades in Russian publications.
Evidence base
Highest evidence
Animal model
Human trial
Studies
4
4
of which in humans
0
2
Effects recorded
4
3
Open conflicts
2
1
Documented adverse events
2
1