Comparison
Cetrorelix vs. Ganirelix
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Research other
Research other
CAS no.
120287-85-6
123246-29-7
Molecular weight
1431.06 g/mol
1570.3 g/mol
Half-life
no data
no data
Sequence
no data
no data
Mechanism of action
Cetrorelix
Cetrorelix competitively and immediately blocks the pituitary GnRH receptor, rapidly suppressing LH and FSH release — without the initial hormone surge ('flare') of GnRH agonists.
Ganirelix
Ganirelix competitively and reversibly binds the pituitary GnRH receptor, rapidly suppressing LH (and, less so, FSH) release — without the initial hormone 'flare' of GnRH agonists.
Evidence base
Highest evidence
Human RCT
Human RCT
Studies
0
1
of which in humans
0
1
Effects recorded
2
2
Open conflicts
0
0
Documented adverse events
1
1
Legal status
Full entries
Frequently asked questions
- What is the difference between Cetrorelix and Ganirelix?
- Cetrorelix is classified as "Research other", while Ganirelix is classified as "Research other". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Ganirelix: Ganirelix is a synthetic decapeptide and GnRH antagonist. In assisted reproduction (IVF) it prevents the premature LH surge during controlled ovarian stimulation. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Cetrorelix or Ganirelix?
- The highest available evidence level is "Human RCT" for Cetrorelix and "Human RCT" for Ganirelix. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Cetrorelix and Ganirelix in Germany and the United States?
- Germany: Cetrorelix — Prescription, Ganirelix — Prescription. United States: Cetrorelix — Prescription, Ganirelix — Prescription. These are factual summaries with source and review date on the individual pages.