Comparison
CJC-1295 vs. Selank
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Growth
Research other
CAS no.
no data
129954-34-3
Molecular weight
3647.3 g/mol
751.85 g/mol
Half-life
144 h
0.3 h
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSR-DACThr-Lys-Pro-Arg-Pro-Gly-ProMechanism of action
CJC-1295
Synthetic analogue of growth-hormone-releasing hormone (GHRH), modified for extended half-life via a Drug Affinity Complex (DAC) binding to albumin. Acts on the pituitary GHRH receptor and stimulates endogenous growth-hormone release.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Evidence base
Highest evidence
Human trial
Human trial
Studies
3
4
of which in humans
2
2
Effects recorded
3
3
Open conflicts
1
0
Documented adverse events
3
1