Epitalon vs. Thymalin

Category

Research other

Healing

CAS no.

307297-39-8

63958-90-7

Molecular weight

390.35 g/mol

1000 g/mol

Half-life

0.3 h

0.5 h

Sequence

Epitalon

Postulated mechanisms include modulation of gene expression in pinealocytes, telomerase activation (observed in cell culture studies) and influence on melatonin synthesis. A defined primary receptor is not established; the mechanistic basis rests on in-vitro and animal data from the Khavinson group.

Thymalin

Thymalin is a complex of multiple polypeptides extracted from bovine or calf thymus. Postulated mechanisms include modulation of T-lymphocyte maturation, influence on interleukin profiles and stimulation of cellular immune response. Being a multi-component preparation, individual mechanisms are difficult to disentangle. Khavinson and colleagues from St Petersburg have described the mechanism over decades in Russian publications.

Highest evidence

Studies

4

4

of which in humans

1

2

Effects recorded

4

3

Open conflicts

1

1

Documented adverse events

1

1