Topic · Indication

Sleep

Sleep latency, slow-wave proportion and subjective recovery. Described preclinically for some peptides (DSIP, GH secretagogues), but controlled human data on clinically relevant endpoints remain limited.

Peptides on this topic

1 peptide researched for this topic

DSIP

Research other · 4 studies

Human trial

Synthetic nonapeptide isolated in 1977 by Guido Monnier and Marcel Schoenenberger from the blood of rabbits in delta sleep. Despite the name, the role in sleep regulation is contested and not confirmed by Western RCTs in larger populations.

Relevant observations

Animal modelEEG changes with increased delta activity after intravenous administration in rabbits originally reported
Human trialShortening of sleep-onset latency reported in a small clinical pilot study in patients with chronic insomnia