Comparison
BPC-157 vs. Thymosin Alpha-1
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Healing
Healing
CAS no.
137525-51-0
62304-98-7
Molecular weight
1419.5 g/mol
3108.32 g/mol
Half-life
4 h
2 h
Sequence
GEPPPGKPADDAGLVAc-SDAAVDTSSEITTKDLKEKKEVVEEAENMechanism of action
BPC-157
Synthetic peptide derived from a sequence of a protein found in gastric juice. In preclinical models, an influence on angiogenic and tissue-protective signalling pathways has been described. The precise molecular mechanisms of action are not conclusively understood.
Thymosin Alpha-1
Thymosin Alpha-1 is an N-terminally acetylated peptide originally isolated from the thymus. It modulates T-lymphocyte maturation and function and acts on dendritic cells via Toll-like receptors (TLR9 / TLR2). In preclinical and some clinical studies, increased interferon-gamma responses and altered T-cell subpopulations have been reported.
Evidence base
Highest evidence
Animal model
Human RCT
Studies
4
2
of which in humans
0
2
Effects recorded
4
3
Open conflicts
2
1
Documented adverse events
2
1