Comparison
Selank vs. Vasopressin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Research other
Research other
CAS no.
129954-34-3
no data
Molecular weight
751.85 g/mol
1084.23 g/mol
Half-life
0.3 h
no data
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Prono data
Mechanism of action
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Vasopressin
Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.
Evidence base
Highest evidence
Human trial
Human RCT
Studies
4
0
of which in humans
2
0
Effects recorded
3
2
Open conflicts
1
0
Documented adverse events
1
1
Legal status
Full entries
Frequently asked questions
- What is the difference between Selank and Vasopressin?
- Selank is classified as "Research other", while Vasopressin is classified as "Research other". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Vasopressin?
- The highest available evidence level is "Human trial" for Selank and "Human RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Vasopressin in Germany and the United States?
- Germany: Selank — Unapproved, Vasopressin — Prescription. United States: Selank — Unapproved, Vasopressin — Prescription. These are factual summaries with source and review date on the individual pages.