Topic · Mechanism

Neuroprotection

Protection of nerve tissue under ischaemia, injury or neurodegenerative stress. Several peptides are studied preclinically (semax, selank); clinical translation is narrowly limited.

Peptides on this topic

1 peptide researched for this topic

Semax

Research other · 4 studies

Human trial

Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent.

Relevant observations

Human trialImprovement of neurological function in acute stroke treatment versus placebo reported in Russian studies