Comparison
CJC-1295 vs. Hexarelin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Growth
Growth
CAS no.
no data
140703-51-1
Molecular weight
3647.3 g/mol
887.05 g/mol
Half-life
144 h
0.9 h
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSR-DACHis-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2Mechanism of action
CJC-1295
Synthetic analogue of growth-hormone-releasing hormone (GHRH), modified for extended half-life via a Drug Affinity Complex (DAC) binding to albumin. Acts on the pituitary GHRH receptor and stimulates endogenous growth-hormone release.
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
Evidence base
Highest evidence
Human trial
Human trial
Studies
4
4
of which in humans
3
3
Effects recorded
3
3
Open conflicts
1
0
Documented adverse events
3
1
Legal status
Full entries
Frequently asked questions
- What is the difference between CJC-1295 and Hexarelin?
- CJC-1295 is classified as "Growth", while Hexarelin is classified as "Growth". CJC-1295: Long-acting synthetic GHRH analogue modified for albumin binding (DAC). Stimulates endogenous growth-hormone release. Pharmacodynamic effect established in small human studies; clinical endpoint trials are missing. Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, CJC-1295 or Hexarelin?
- The highest available evidence level is "Human trial" for CJC-1295 and "Human trial" for Hexarelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of CJC-1295 and Hexarelin in Germany and the United States?
- Germany: CJC-1295 — Unapproved, Hexarelin — Unapproved. United States: CJC-1295 — Research only, Hexarelin — Unapproved. These are factual summaries with source and review date on the individual pages.