Lexicon
Peptides A–Z
All catalogued peptides alphabetically. Filter by evidence tier or click a letter.
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Filtered: only peptides with at least one observation at tier “Human trial” · 58Clear filter ×
A2
Afamelanotide
Human RCTResearch other · Scenesse
Afamelanotide (brand name Scenesse) is a synthetic 13-amino-acid analogue of α-melanocyte-stimulating hormone (α-MSH) and a melano…
Argireline
Human trialCosmetic · Acetyl Hexapeptide-3
Synthetic hexapeptide marketed as a topical anti-wrinkle ingredient (e.g. by Lipotec/Lubrizol). Mechanism modelled on the SNAP-25-…
B2
Bremelanotide
Human RCTResearch other · PT-141
Synthetic cyclic heptapeptide acting as a non-selective melanocortin-receptor agonist. FDA-approved in 2019 as Vyleesi for hypoact…
Buserelin
Human RCTResearch other · Suprefact
Buserelin is a synthetic GnRH agonist (including as a nasal spray). It is used in endometriosis, hormone-dependent prostate cancer…
C5
CagriSema
Human RCTMetabolic · Cagrilintid/Semaglutid
CagriSema is a fixed-dose combination of the amylin analogue cagrilintide and the GLP-1 agonist semaglutide (Novo Nordisk), in lat…
Calcitonin (Lachs)
Human RCTResearch other · Salmon Calcitonin
Salmon calcitonin is a synthetically produced 32-amino-acid peptide hormone that corresponds to the body's own calcitonin but exhi…
Carbetocin
Human RCTResearch other · Duratocin
Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injec…
Cetrorelix
Human RCTResearch other · Cetrotide
Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH sur…
CJC-1295
Human trialGrowth · CJC-1295 mit DAC
Long-acting synthetic GHRH analogue modified for albumin binding (DAC). Stimulates endogenous growth-hormone release. Pharmacodyna…
D3
Degarelix
Human RCTResearch other · Firmagon
Degarelix (trade name Firmagon) is a synthetic decapeptide and a gonadotropin-releasing hormone (GnRH) receptor antagonist. Unlike…
Desmopressin
Human RCTResearch other · DDAVP
Desmopressin (DDAVP) is a synthetic analogue of the endogenous hormone vasopressin (antidiuretic hormone, ADH). Deamination of the…
DSIP
Human trialResearch other · Delta Sleep Inducing Peptide
Synthetic nonapeptide isolated in 1977 by Guido Monnier and Marcel Schoenenberger from the blood of rabbits in delta sleep. Despit…
E4
Elamipretide
Human RCTResearch other · SS-31
Elamipretide (SS-31, MTP-131, formerly Bendavia) is a synthetic, mitochondria-targeting tetrapeptide (sequence D-Arg-Dmt-Lys-Phe-N…
Eloralintide
Human RCTMetabolic · LY3841136
Eloralintide is a selective, long-acting amylin receptor agonist from Eli Lilly for once-weekly subcutaneous use — under investiga…
Enfuvirtid
Human RCTResearch other · Enfuvirtide
Enfuvirtide is a synthetic 36-amino-acid peptide and the first HIV-1 fusion inhibitor. It binds the HR1 region of the viral envelo…
Epitalon
Human trialResearch other · Epithalon
Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin (V. Khavinson, St. Petersburg). Investigated …
F1
G8
Ganirelix
Human RCTResearch other · Orgalutran
Ganirelix is a synthetic decapeptide and GnRH antagonist. In assisted reproduction (IVF) it prevents the premature LH surge during…
GHK-Cu
Human trialCosmetic · Copper Tripeptide-1
Endogenous tripeptide (glycyl-L-histidyl-L-lysine) that chelates copper(II) ions. Studied in skin models and small human trials on…
GHRP-2
Human trialGrowth · Pralmorelin
Synthetic hexapeptide of the GH secretagogue family. Approved in Japan as GHRP Kaken as a diagnostic test for GH deficiency. Not a…
GHRP-6
Human trialGrowth · Growth Hormone Releasing Peptide 6
Synthetic hexapeptide that founded the class of growth-hormone-releasing peptides (GHRPs). Cyril Bowers identified GHRP-6 in the l…
Glepaglutide
Human RCTResearch other · ZP1848
Glepaglutide is a long-acting GLP-2 analogue (Zealand Pharma) intended to reduce the need for parenteral support in short bowel sy…
Glucagon
Human RCTMetabolic · Glukagon
Glucagon is a 29-amino-acid pancreatic hormone produced by the alpha cells of the islets of Langerhans. It is the physiological co…
Gonadorelin
Human trialResearch other · GnRH
Gonadorelin is the synthetic decapeptide with an amino-acid sequence identical to endogenous gonadotropin-releasing hormone (GnRH/…
Goserelin
Human RCTResearch other · Zoladex
Goserelin is a synthetic decapeptide and an agonist of gonadotropin-releasing hormone (GnRH). The medical literature describes it …
H3
Hexarelin
Human trialGrowth · HEX
Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and …
Histrelin
Human RCTResearch other · Supprelin LA
Histrelin is a nonapeptide GnRH agonist delivered as a once-yearly implant. Approved for central precocious puberty in children (S…
Humanin
Human trialResearch other · HN
Humanin is a 24-amino-acid mitochondrial-encoded peptide (mitochondrial-derived peptide, MDP) whose open reading frame lies within…
I1
K1
L3
Leuprorelin
Human RCTResearch other · Leuprolide
Leuprorelin (also leuprolide) is a synthetic nonapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH). It is an approved…
Linaclotid
Human RCTResearch other · Linaclotide
Linaclotide is a 14-amino-acid peptide and guanylate cyclase-C (GC-C) agonist. It is approved for irritable bowel syndrome with co…
LL-37
Human trialResearch other · Cathelicidin LL-37
LL-37 is the only known human cathelicidin, a 37-amino-acid antimicrobial peptide generated by cleavage of the precursor protein h…
M5
Matrixyl
Human RCTCosmetic · Palmitoyl Pentapeptide-4
Synthetic pentapeptide (KTTKS) with a palmitoyl modification, marketed as a topical anti-aging ingredient (Lipotec/Sederma). Struc…
Mazdutide
Human RCTMetabolic · IBI362
Synthetic oxyntomodulin analogue that simultaneously activates the GLP-1 and glucagon receptors (dual agonist). Developed by Innov…
Melanotan II
Human trialResearch other · MT-II
Cyclic hepta-peptide and non-selective melanocortin-receptor agonist. Originally researched at the University of Arizona as a sun-…
Mod GRF (1-29)
Human trialGrowth · Modified GRF 1-29
Tetrasubstituted synthetic analogue of GHRH(1-29), traded on the grey market as "CJC-1295 without DAC". Closely related to sermore…
MOTS-c
Human trialResearch other · Mitochondrial ORF of the 12S rRNA type-c
MOTS-c is a 16-amino-acid mitochondrial-encoded peptide (mitochondrial-derived peptide, MDP) whose open reading frame lies within …
N1
O1
P2
Pemvidutide
Human trialMetabolic · ALT-801
Pemvidutide is a 29-amino-acid GLP-1/glucagon dual receptor agonist (Altimmune) under investigation for obesity and the fatty-live…
Pramlintid
Human RCTMetabolic · Pramlintide
Pramlintide is a synthetic analog of the hormone amylin. It is used as an adjunct to mealtime insulin therapy in type 1 and type 2…
S7
Sekretin
Human trialResearch other · Secretin
Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnos…
Selank
Human trialResearch other · TP-7
Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western pha…
Semax
Human trialResearch other · MEHFPGP
Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for isc…
Sermorelin
Human RCTGrowth · GHRH(1-29)
Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Fo…
Setmelanotide
Human RCTMetabolic · Imcivree
Setmelanotide (brand name Imcivree) is a synthetic cyclic octapeptide and an agonist at the melanocortin-4 receptor (MC4R). It was…
Sincalide
Human trialResearch other · Kinevac
Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimula…
SNAP-8
Human trialCosmetic · Acetyl Octapeptide-3
Synthetic octapeptide marketed as a topical anti-wrinkle ingredient (Centerchem/Lipotec). Structurally related to Argireline (Acet…
T7
Teduglutid
Human RCTResearch other · Teduglutide
Teduglutide is a DPP-4-resistant analog of GLP-2 (glucagon-like peptide-2). It promotes growth and function of the intestinal muco…
Terlipressin
Human RCTResearch other · Terlivaz
Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrict…
Thymalin
Human trialHealing · Vilon (verwandtes Di-Peptid)
Complex of low-molecular polypeptides extracted from calf thymus. Approved in Russia since the 1970s as an immunomodulator. The ex…
Thymosin Alpha-1
Human RCTHealing · TA1
Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (…
Thymosin Beta-4
Human trialHealing · TB4
Thymosin Beta-4 (Tβ4) is an endogenous 43-amino-acid peptide regarded as the principal intracellular actin-sequestering factor, in…
Tirzepatide
Human RCTMetabolic · LY3298176
Synthetic peptide that simultaneously activates the GLP-1 and GIP receptor (dual agonist). Approved in the US and EU for type 2 di…
Triptorelin
Human RCTResearch other · Decapeptyl
Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since…
V2
Vasopressin
Human RCTResearch other · Arginin-Vasopressin
Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vasc…
VK2735
Human RCTMetabolic · VK2735 (Viking)
VK2735 is a dual GLP-1/GIP receptor agonist from Viking Therapeutics, in development in both subcutaneous and oral forms for obesi…