Лексикон
Пептиды А–Я
Все каталогизированные пептиды в алфавитном порядке. Фильтруйте по уровню доказательности или выберите букву.
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A4
Abaloparatid
РКИ на людяхИсследования (прочее) · Abaloparatide
Abaloparatide is a synthetic 34-amino-acid analogue of parathyroid hormone-related protein (PTHrP 1-34). It is regulatory-approved…
Afamelanotide
РКИ на людяхИсследования (прочее) · Scenesse
Afamelanotide (brand name Scenesse) is a synthetic 13-amino-acid analogue of α-melanocyte-stimulating hormone (α-MSH) and a melano…
Amycretin
РКИ на людяхМетаболизм · NN0487
Amycretin is a unimolecular GLP-1 and amylin receptor agonist from Novo Nordisk — in development both as a once-weekly subcutaneou…
AOD-9604
РКИ на людяхРост · HGH Fragment 176-191
Synthetic 16-amino-acid peptide corresponding to the C-terminal fragment of human growth hormone (hGH 176-191). Originally develop…
B2
Bremelanotide
РКИ на людяхИсследования (прочее) · PT-141
Synthetic cyclic heptapeptide acting as a non-selective melanocortin-receptor agonist. FDA-approved in 2019 as Vyleesi for hypoact…
Buserelin
РКИ на людяхИсследования (прочее) · Suprefact
Buserelin is a synthetic GnRH agonist (including as a nasal spray). It is used in endometriosis, hormone-dependent prostate cancer…
C6
Cagrilintide
РКИ на людяхМетаболизм · AM833
Synthetic long-acting amylin analog being developed in combination with semaglutide (CagriSema). Phase 3 trials for obesity and ty…
CagriSema
РКИ на людяхМетаболизм · Cagrilintid/Semaglutid
CagriSema is a fixed-dose combination of the amylin analogue cagrilintide and the GLP-1 agonist semaglutide (Novo Nordisk), in lat…
Calcitonin (Lachs)
РКИ на людяхИсследования (прочее) · Salmon Calcitonin
Salmon calcitonin is a synthetically produced 32-amino-acid peptide hormone that corresponds to the body's own calcitonin but exhi…
Carbetocin
РКИ на людяхИсследования (прочее) · Duratocin
Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injec…
Cerebrolysin
РКИ на людяхИсследования (прочее) · FPF-1070
Cerebrolysin (FPF-1070) is not a single peptide but a porcine-brain-derived preparation of low-molecular-weight peptides and free …
Cetrorelix
РКИ на людяхИсследования (прочее) · Cetrotide
Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH sur…
D3
Degarelix
РКИ на людяхИсследования (прочее) · Firmagon
Degarelix (trade name Firmagon) is a synthetic decapeptide and a gonadotropin-releasing hormone (GnRH) receptor antagonist. Unlike…
Desmopressin
РКИ на людяхИсследования (прочее) · DDAVP
Desmopressin (DDAVP) is a synthetic analogue of the endogenous hormone vasopressin (antidiuretic hormone, ADH). Deamination of the…
Dulaglutide
РКИ на людяхМетаболизм · LY2189265
GLP-1 receptor agonist designed as a fusion protein of two modified GLP-1(7-37) sequences covalently linked to a human IgG4-Fc fra…
E6
Ecnoglutide
РКИ на людяхМетаболизм · XW003
Ecnoglutide (XW003) is a long-acting, cAMP-signalling-biased GLP-1 analogue from Sciwind Biosciences. Derived from GLP-1(7-37) wit…
Efinopegdutide
РКИ на людяхМетаболизм · MK-6024
Efinopegdutide (MK-6024, formerly JNJ-64565111 / HM12525A) is a once-weekly dual agonist at the GLP-1 and glucagon receptors, deve…
Elamipretide
РКИ на людяхИсследования (прочее) · SS-31
Elamipretide (SS-31, MTP-131, formerly Bendavia) is a synthetic, mitochondria-targeting tetrapeptide (sequence D-Arg-Dmt-Lys-Phe-N…
Eloralintide
РКИ на людяхМетаболизм · LY3841136
Eloralintide is a selective, long-acting amylin receptor agonist from Eli Lilly for once-weekly subcutaneous use — under investiga…
Enfuvirtid
РКИ на людяхИсследования (прочее) · Enfuvirtide
Enfuvirtide is a synthetic 36-amino-acid peptide and the first HIV-1 fusion inhibitor. It binds the HR1 region of the viral envelo…
Exenatide
РКИ на людяхМетаболизм · AC2993
Synthetic version of exendin-4, originally isolated from the saliva of the Gila monster (Heloderma suspectum). First GLP-1 recepto…
G4
Ganirelix
РКИ на людяхИсследования (прочее) · Orgalutran
Ganirelix is a synthetic decapeptide and GnRH antagonist. In assisted reproduction (IVF) it prevents the premature LH surge during…
Glepaglutide
РКИ на людяхИсследования (прочее) · ZP1848
Glepaglutide is a long-acting GLP-2 analogue (Zealand Pharma) intended to reduce the need for parenteral support in short bowel sy…
Glucagon
РКИ на людяхМетаболизм · Glukagon
Glucagon is a 29-amino-acid pancreatic hormone produced by the alpha cells of the islets of Langerhans. It is the physiological co…
Goserelin
РКИ на людяхИсследования (прочее) · Zoladex
Goserelin is a synthetic decapeptide and an agonist of gonadotropin-releasing hormone (GnRH). The medical literature describes it …
H1
I2
Icatibant
РКИ на людяхИсследования (прочее) · Firazyr
Icatibant is a synthetic decapeptide and selective antagonist of the bradykinin B2 receptor. It is approved to treat acute attacks…
Ipamorelin
РКИ на людяхРост · NNC 26-0161
Synthetic pentapeptide and selective growth-hormone secretagogue. Developed at Novo Nordisk in the 1990s as a pentapeptide GHRP su…
K1
L5
Lanreotid
РКИ на людяхИсследования (прочее) · Lanreotide
Lanreotide is a synthetic cyclic octapeptide analog of somatostatin. It binds preferentially to the somatostatin receptors SSTR2 a…
Leuprorelin
РКИ на людяхИсследования (прочее) · Leuprolide
Leuprorelin (also leuprolide) is a synthetic nonapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH). It is an approved…
Linaclotid
РКИ на людяхИсследования (прочее) · Linaclotide
Linaclotide is a 14-amino-acid peptide and guanylate cyclase-C (GC-C) agonist. It is approved for irritable bowel syndrome with co…
Liraglutide
РКИ на людяхМетаболизм · NN2211
GLP-1 receptor agonist with a half-life of about 13 hours. The first daily (not weekly) modern GLP-1 RA — approved as Victoza for …
Lixisenatide
РКИ на людяхМетаболизм · AVE0010
Synthetic exendin-4 analog with a C-terminal lysine extension. Prandial GLP-1 RA focused on postprandial glucose. FDA-approved 201…
M3
Maridebart Cafraglutide
РКИ на людяхМетаболизм · MariTide
Maridebart cafraglutide (MariTide, Amgen) is a bispecific molecule: a GLP-1 receptor agonist combined with a GIP receptor antagoni…
Matrixyl
РКИ на людяхКосметика · Palmitoyl Pentapeptide-4
Synthetic pentapeptide (KTTKS) with a palmitoyl modification, marketed as a topical anti-aging ingredient (Lipotec/Sederma). Struc…
Mazdutide
РКИ на людяхМетаболизм · IBI362
Synthetic oxyntomodulin analogue that simultaneously activates the GLP-1 and glucagon receptors (dual agonist). Developed by Innov…
N1
O2
Octreotide
РКИ на людяхИсследования (прочее) · SMS 201-995
Synthetic octapeptide somatostatin analog with a longer half-life than endogenous somatostatin. FDA- and EMA-approved since the 19…
Oxytocin
РКИ на людяхИсследования (прочее) · OXT
Oxytocin is an endogenous nonapeptide hormone of the posterior pituitary. In synthetic form (Pitocin, Syntocinon) it has been appr…
P4
Pasireotid
РКИ на людяхИсследования (прочее) · Pasireotide
Pasireotide is a multireceptor somatostatin analog binding to four of the five somatostatin receptors (especially SSTR5). It is ap…
Petrelintide
РКИ на людяхМетаболизм · ZP8396
Petrelintide is a long-acting amylin analogue (Zealand Pharma, with Roche) for once-weekly subcutaneous use — developed for weight…
Plecanatid
РКИ на людяхИсследования (прочее) · Plecanatide
Plecanatide is a 16-amino-acid analog of the body's own uroguanylin and a guanylate cyclase-C (GC-C) agonist. It is approved for c…
Pramlintid
РКИ на людяхМетаболизм · Pramlintide
Pramlintide is a synthetic analog of the hormone amylin. It is used as an adjunct to mealtime insulin therapy in type 1 and type 2…
R1
S4
Semaglutid
РКИ на людяхМетаболизм · Semaglutide
Long-acting GLP-1 receptor agonist. Approved as a medicinal product for type-2 diabetes (Ozempic, Rybelsus), chronic weight manage…
Sermorelin
РКИ на людяхРост · GHRH(1-29)
Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Fo…
Setmelanotide
РКИ на людяхМетаболизм · Imcivree
Setmelanotide (brand name Imcivree) is a synthetic cyclic octapeptide and an agonist at the melanocortin-4 receptor (MC4R). It was…
Survodutide
РКИ на людяхМетаболизм · BI 456906
Synthetic peptide that simultaneously activates the GLP-1 and glucagon receptors. Developed by Boehringer Ingelheim and Zealand Ph…
T7
Teduglutid
РКИ на людяхИсследования (прочее) · Teduglutide
Teduglutide is a DPP-4-resistant analog of GLP-2 (glucagon-like peptide-2). It promotes growth and function of the intestinal muco…
Teriparatid
РКИ на людяхИсследования (прочее) · Teriparatide
Teriparatide is the recombinant N-terminal fragment 1-34 of human parathyroid hormone (PTH). It is regulatory-approved and studied…
Terlipressin
РКИ на людяхИсследования (прочее) · Terlivaz
Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrict…
Tesamorelin
РКИ на людяхРост · TH9507
Stabilised GHRH analog (growth-hormone-releasing hormone). FDA-approved in 2010 as Egrifta for reduction of abdominal lipohypertro…
Thymosin Alpha-1
РКИ на людяхЗаживление · TA1
Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (…
Tirzepatide
РКИ на людяхМетаболизм · LY3298176
Synthetic peptide that simultaneously activates the GLP-1 and GIP receptor (dual agonist). Approved in the US and EU for type 2 di…
Triptorelin
РКИ на людяхИсследования (прочее) · Decapeptyl
Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since…
V2
Vasopressin
РКИ на людяхИсследования (прочее) · Arginin-Vasopressin
Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vasc…
VK2735
РКИ на людяхМетаболизм · VK2735 (Viking)
VK2735 is a dual GLP-1/GIP receptor agonist from Viking Therapeutics, in development in both subcutaneous and oral forms for obesi…